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dermatology causes pulmonary algorithm anca classification cutaneous joint pain signs skin aortitis associated behcet canca cardiology clinical conditions cryoglobulinemia cryoglobulins
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
>>> MPA > eGPA ... ): eGPA, MPA >>> ... #differential # ... diagnosis #algorithm ... #rheumatology
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (EGPA ... PR3 Anti-GBM disease ... #PR3 #Diagnosis ... #Rheumatology
ILD of Known Cause - Differential Diagnosis Exposure: • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis • Treatment Related:
Known Cause - Differential ... Diagnosis Exposure ... Granulomatous DX with Vasculitis ... : GPA, EGPA • ... #Diagnosis #interstitial
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... > PR3 60% • GPA ... • ANCA (Dx: GPA ... differential #diagnosis ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... polyangiitis - EGPA ... - GPA Cutaneous ... : • Behcet Disease ... #dermatology #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated Vasculitis ... polyangiitis (GPA ... #differential # ... diagnosis #algorithm ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - GPA - EGPA ... - MPA • CTD ... #Diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... Diagnosis: Vasculitis ... #Polyangiitis #GPA
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Diagnosis Framework ... in 24h Airway disease ... Kaposi's sarcoma • Rheumatologic ... Autoimmune: ANCA-Assoc vasculitis ... (GPA > EGPA, MPA
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... (5%): PAN > GPA ... , EGPA • Solid ... signs #lesions #diagnosis ... pathology #lesions #differential
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