16 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... >>> MPA > eGPA ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Sarcoidosis • GPA ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
capillaritis • EGPA ... inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Differential Diagnosis ... polyangiitis • EGPA ... dermatology #rash #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... phenomenon (20%) Joints ... signs #symptoms #diagnosis ... #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
- Diagnosis, causes ... and management ... involvement - Joint ... #Rheumatology # ... #Management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... classification #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... especially in the wrists ... many differential diagnoses ... #diagnosis #sle ... erythematosus #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Lyme disease, Vasculitis ... Heberden's nodes (DIP joints ... #differential #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... #Rheumatology