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differential management symptoms causes dermatology erythematosus lupus workup autoimmune classification disease generalized myositis pruritus secondary sle vasculitis abnormal activation alopecia
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... distal to elbows/wrists ... skin thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... Liver Function Tests ... Myelodisplastic syndrome ... #Algorithm #causes
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Myelodysplastic Syndromes ... Liver Function Tests ... #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Positive pathergy test ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
algorithm. ... clinical symptoms/signs ... presence of metabolic syndrome ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... with lymphatic system ... Amy Chung, MD, MSc ... pathophysiology #Hematology
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