17 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... - CRP: Usually normal ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... is a skin prick test ... #management #signs ... #symptoms #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... cascade is intact - test ... inhibitor and lupus ... discern these causes ... #Hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Examine for signs ... Casey Albin MD @ ... #PhysicalExam #neurology ... #comatose #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... such as systemic lupus ... purpura: strong sign ... retinopathy Lab Tests ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology