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Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Systemic Lupus Erythematosus ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Scapholunate Dissociation
The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
"Terry Thomas" sign ... to diagnosis scapholunate ... ("Terry Thomas sign ... box, pain with wrist ... #Orthopedics #Sports
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
- Differential Diagnosis ... Algorithm Erythrematous ... Auspitz sign, Koebner's ... flat-topped) papules on wrists ... #Differential #Diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Hydroxychloroquine *Short ... Systemic #Lupus #Erythematosus ... #SLE #Summary #diagnosis ... #rheumatology #
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
"pooping duck sign ... "pooping duck sign ... ulna, pain with wrist ... Radiology #XRay #Diagnosis ... #Orthopedics #Sports
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... Systemic #Lupus #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... • Malar rash - spares ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... #Diagnosis #Management ... #Summary #rheumatology