37 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... distal to elbows/wrists ... #SSc #rheumatology ... #diagnosis #signs ... #workup
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
sclerosis/polymyositis ... Treatment: • ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and treatment can ... • Multiple sclerosis ... BEE #Syndromes #neurology ... #differential #diagnosis
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm
Action Tremor - Occurs During Voluntary Muscle
- Differential Diagnosis ... stroke, multiple sclerosis ... ) Resting Tremor ... palsy • Multiple System ... MovementDisorders #Neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Immune Complex: Systemic ... sclerosis • Anti-Glomerular ... testing: anti-ANCA ... #nephrology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... Treatment: • ... taper 3-7 days - Short ... #neurology #treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... IgG4 #Related #Disease ... #phenotypes #workup ... #treatment #rheumatology
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
• Typhoidal: Systemic ... : Serology (preferred ... Culture & GS, PCR Treatment ... : • Severe Disease ... #management #treatment