13 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... ) Pathophysiology ... : • Defect in fetal ... #hepatology #obstetrics
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... (AFLP) Three syndromes ... coagulation defects. 1) ... #obstetrics #hematology ... #diagnosis #table
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... (AFLP) • Onset ... #hepatology #obstetrics ... #differential #diagnosis ... #icp #HELLP #AFLP
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
pruritus after pregnancy ... criteria are met: 1. ... Elevated ALP 2. ... Positive AMA or ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... - Half-life: 1 ... #differential #diagnosis ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Female:Male 9:1 ... 65 years PBC Pathophysiology ... obstruction • ALP ... cholestasis of pregnancy ... #workup #hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... At least 3 of (Acute ... heart failure, positive ... #diagnosis #comparison
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... on ABx) → Acute ... Perforation) Pathophysiology ... Epidemiology: • #1 ... 10 mg/kg IV x 1
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Overview Normal: < 1% ... Clinically significant ... odds of having positive ... likelihood of negative clinical ... #pathophysiology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... Sweet Syndrome (Acute ... Major criteria 1. ... inflammatory disease, or pregnancy ... rate >20 mm/h; positive