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diagnosis hematology causes algorithm hemolysis obgyn pathophysiology acidosis aflp agglutinin cardiology cardiomyopathy cbc classification cold dehydrogenase disease elevated elevation extravascular
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Normal RBCs • Acute ... Hypothyroid • Pregnancy ... #Normocytic #Anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... immune-complex hemolytic anemia ... • Acute HTR ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Microangiopathic hemolytic anemia ... - Pernicious anemia ... - Prosthetic valves
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... infiltration) Differential ... #hepatology #obstetrics
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
If the value is ... result in severe anemia ... immune hemolytic anemia ... elevation Serum lactate ... WBC count and differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... cardiac output - Acute ... peritonitis - Acute ... 30mmHg) - Severe anemia
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... -0/abstract BANDemia ... appreciate the value ... Degree of bandemia ... bacteremia • Bandemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... disease #hemolytic #anemia
Peripartum Cardiomyopathy (PPCM) What is PPCM? • A form of acute systolic heart failure that develops late in
• A form of acute ... maternal age • Anemia ... Cesarean delivery Clinical ... Key Point: High clinical ... , selenium) Differential
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