14 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty ... Liver of Pregnancy ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... #Pregnancy #hepatology ... #obstetrics #obgyn
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pregnancy Intrahepatic ... Cholestasis of Pregnancy ... necrosis HELLP Syndrome ... and hemorrhage Acute ... #hepatology #obstetrics
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Autoimmune hepatitis, Acute ... obstruction, HELLP Syndrome ... Toxic: Medication, Pregnancy ... #algorithm #hepatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
for Sweet Syndrome ... (Acute Febrile ... inflammatory disease, or pregnancy ... Abnormal laboratory values ... #Diagnosis #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... • Cirrhosis/acute ... sarcoidosis) • Liver ... of pregnancy ... Diagnosis #causes #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... pregnancy 3. ... #differential #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Hepatocellular - Check Acute ... Mixed - Check Acute ... • Gilbert's syndrome ... #differential #Hepatology