18 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... pruritus after pregnancy ... Diagnose PBC if 2/3 criteria ... #PBC #Primary #Biliary ... Diagnosis #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Drugs - Pregnancy ... Drugs - Primary biliary ... PSC - Other biliary ... Diagnosis #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
hepatitis, Acute biliary ... Toxic: Medication, Pregnancy ... Extrahepatic • Biliary ... Acute #algorithm #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
the liver ALP - Biliary ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
LFTs) - Normal Values ... (GGT) - Liver, biliary ... Conjugated/DBili) - Biliary ... LFTs #Laboratory #Values ... Interpretation #diagnosis #hepatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... an underlying hematologic ... inflammatory disease, or pregnancy ... Abnormal laboratory values ... #Diagnosis #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
AIH, Wilsons, Pregnancy ... - CBD stone, Biliary ... Algorithm #diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... : • Defect in fetal ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... No extrahepatic biliary ... cholestasis of pregnancy ... malignancy #Primary #Biliary ... diagnosis #workup #hepatology