11 results
diagnosis management differential oncology myelodysplastic thrombocytopenia algorithm anemia blood clinical disorders essential et gangrenosum hemeonc hemophagocytic hemophilia hlh lymphohistiocytosis myelodysplasia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... • Allogeneic stem ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... hematopoietic stem ... Hypocellular/Hypoplastic MDS ... anemia Treatment ... Anemia #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Infection exposure (l MD ... Risks factor for HIV ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... by a hemophilia treatment ... Avoid meds that ... #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... hypertension and/or drug treatment ... Constitutional disorders, eg ... white blood cell aplasia ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... hematopoietic stem ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... thrombocytosis (e.g ... PV, MDS, CML) Treatment ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... due to marrow aplasia ... Extremely rare - HIV ... by Nick Mark MD ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
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