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diagnosis differential management coagulation abnormal prolonged pt thrombocytopenia treatment algorithm arterial blood common comparison dic disorders disseminated distribution embolism erythema
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Drugs (antibiotics e.g ... Viral: HSV, EBV, HIV ... Nodosum #Mnemonic #Causes ... Differential #Diagnosis #Dermatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
the PT and the aPTT ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Quinidine • HIT ... Foreign Surface (e.g ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Risks factor for HIV ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... Study #diagnosis #hematology ... #hematology #laboratory
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... hemophilia type (e.g ... Management #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hematological: - HIT ... thrombosis in young ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
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