16 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) • Advanced Liver ... Autoimmune disorders (e.g ... comparison #diagnosis #hematology
Liver Mass - Differential Diagnosis Algorithm
Benign Cystic 
 • Cyst
 • Polycystic Liver Disease
 • Caroli's
Liver Mass - Differential ... • Polycystic Liver ... • Metastases (e.g ... #Mass #Hepatology ... Diagnosis #Algorithm #Causes
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology ... #coagulation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... Renal Disease, Liver ... Reticulocytosis • Liver ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... function test, ANA (e.g ... bypass), LFT (liver ... or if a primary hematologic ... #Workup #hematology