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diagnosis management differential syndrome algorithm medications table action barre clinical gravis guillain hypernatremia myasthenia nephron polyuria sclerosis sites abortive als
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
(e.g. mannitol) ... (e.g. furosemide ... (e.g. ... #pharmacology # ... nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
Pathophysiology - Diuretic ... Sites of Action Diuretics ... ) Loop agents (eg ... Sites #Action #nephrology ... #pharmacology
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... administration • Osmotic diuresis ... Polyuria scheme) e.g ... Hypernatremia #Nephrology ... Diagnosis #Algorithm #Causes
Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
Causes of Polyuria ... a.k.a. osmotic diuresis ... : Conventional diuretics ... SGLT2 inhibitors (e.g ... #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... Kidney stones caused ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... heparinized tube) • ECG ... only if no clear cause ... Terbutaline 7 µg/kg ... #potassium #nephrology
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Treatment: anticholinergics ... PhysicalExam #clinical #neurology
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 Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
Causes of Polyuria ... /min) Osmotic Diuresis ... concentration (e.g ... #Polyuria #Nephrology ... Diagnosis #Algorithm #Causes
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
metastases, Infection (e.g ... (e.g., hypokalemia ... disease, Drugs (e.g ... Treatment is aimed ... Classification #Types #Nephrology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Presentation - Young ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual ... diagnosis #management #neurology
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