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diagnosis management algorithm hematology nephrology classification cardiology syndromes workup infectiousdiseases pediatrics peds pulmonary secondary signs symptoms systemic thrombocytopenia acute barre
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #differential #
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... • Secondary (e.g ... #Differential # ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Chronic Disease (e.g ... Classification #Differential ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Iron Deficiency (Eg ... Other • e.g ... #Hematology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
bilirubin production (eg ... , hemolytic anemias ... uptake and storage (eg ... (eg, spirochetal ... #unconjugated #differential
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... • Infection (e.g ... Brain lesions (e.g ... #diagnosis #neurology ... #differential
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - Differential ... Dysplasias • (e.g ... Panhypopituitarism Treatment ... #ShortStature #Differential ... endocrinology #causes
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