27 results
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... • CNS: parietal ... • Infection (e.g ... Brain lesions (e.g ... #diagnosis #neurology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephritic syndrome—due ... RBC casts in urine ... May be 10 (eg direct ... #Classification ... #Proteinuria #Nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... AIN) • Drugs (e.g ... Differential #Diagnosis #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... #symptoms #signs
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Pathophysiology: ... pleurothotonus #PhysicalExam
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... • Meningeal signs ... (e.g., fever, myalgia ... brain lesion • CNS ... infection (e.g.
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
Holmes-Adie Syndrome ... Hyporeflexia • Young ... Diagnosis: • CN ... dissociation • Other causes ... #Adies #Pupil #PhysicalExam
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Presentation - Young ... • Or brainstem syndromes ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... Non-inflammatory causes ... skull neoplasms (e.g ... #neurology #noninflammatory