12 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... presents in thrombocytopenic ... palpable, the differential ... While all patients ... #Diagnosis #Dermatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... and first-line treatment ... #purpura #TTP # ... #Comparison #Diagnosis ... #Table #Hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
: - Catch-all term ... red-flags to exclude dermatologic ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential ... #Ddxof
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Gangrenosum, NEH T - Treatment ... Coagulopathy: Purpura ... fulminans/DIC, Thrombocytopenia ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... + Bleeding Treatment ... diagnosis #causes #treatment
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
considered in all ... Heparin-induced thrombocytopenia ... other causes of purpura ... Venous #Arterial #pathophysiology ... #hematology #differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... Management: • D/c all ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Renal Failure Treatment
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... the mainstay of treatment ... multiple myeloma or AL ... #Diagnosis #comparison ... #table #dermatology