12 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... autoantibodies #signs ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ACLE) • Erythematous ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... search ANA and aPL ... clues #system #erythematosus ... #rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
scale on elbows & knees ... Auspitz sign, Koebner's ... soles • Discoid Lupus ... Erythematous - ... #Differential #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus ( ... life-threatening • Treatment ... #sle #comparison ... #table #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... diagnosis #management #hematology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... erythematosus. ... Pericarditis #Symptoms #Signs ... #Presentation #comparison
Holistic Management of Systemic Lupus
 • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Management of Systemic Lupus ... Antimalarials for all ... #Erythematosus ... #management #treatment ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
present, symptoms, signs ... Splenomegaly Treatment ... transformation into AML ... • Treatment is ... #hematology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... Erythematosus ... for 1 year of treatment ... pharmacology #risk #differential ... #diagnosis #rheumatology