16 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... reticularis Differential ... • Goodpasture syndrome ... • Angiocentric lymphoma ... rash #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
scleroderma) - Anti-Scl ... seen in 30—70% of cases ... • Sjögren syndrome ... ANCA+ 90% • Granulomatosis ... antibodies #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... #Lymphopenia #ICL ... #Differential # ... Causes #lymphocytopenia
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... (90-95% of cases ... Immunohistochemical studies (to differentiate ... Treatment • Early ... classification #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
SCC or Hodgkin lymphoma ... muscles: “myasthenic crises ... life-threatening Differential ... : - Bedside: ice ... Myasthenia Crises
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... organ dysfuxtion, ICU
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology
Iliotibial Band Friction Syndrome - MSK Radiology
Imaging Findings:
 • The iliotibial band (ITB) is thickened with
Band Friction Syndrome ... Case description ... • Treatment: Conservative ... Differential diagnosis ... ITBand #Friction #Syndrome