8 results
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm Idiopathic ... ), Heme malig (AML ... CML, T-cell leuk/lymphoma ... , B-cell lymphomas
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... organ dysfuxtion, ICU
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
(ICL) / Lymphocytopenia ... DIAGNOSTIC CRITERIA FOR ICL ... Unc119) • Heme (lymphoma ... #Lymphopenia #ICL ... #Differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Cell Leukemia • Idiopathic ... Significance (ICUS) • Idiopathic ... blood count with differential ... progression to AML
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Angioimmunoblastic T-cell lymphoma ... La, anti-Jo-1, SCL
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
distinct subtype of idiopathic ... Idiopathic MCD without ... with interleukin (IL ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology