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diagnosis nephrology review differential management table renal causes comparison high pathophysiology treatment 8as agents aldosterone algorithm amikacin aminoglycosides anaerobe anaerobic
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... Medications 2. ... diagnosis #causes #potassium
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... of aspiration #Potassium ... #medications #pharmacology
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
(PO and IV) - Antibiotics ... Class Overview ... Spectrum: covers all ... infections #Pharmacology ... #Antibiotics #Review
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... Medications 2. ... diagnosis #causes #potassium
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... 30S inhibitor (all ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview Mechanism: Glycopeptide - inhibits cell wall synthesis
) - Antibiotics ... Class Overview ... Used for: all sorts ... #Pharmacology #Antibiotics ... #Review #Overview
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
) MECHANISM: Potassium ... patiromer) is a potassium ... ACE inhibitors, ... Veltassa #Patiromer #Potassium ... #Pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
with excreting potassium ... Antagonists), all ... avoid harmful hyperkalemia ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
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