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management oncology rheumatology activetb causes chronic latenttb syndrome tb tuberculosis abscess aclf acquired acute adultonset algorithm apml arteritis cap cirrhosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure (ACLF ... ) Clinical Guidelines ... ACLF = possibly ... EmoryGastroHep #ACLF ... #gastroenterology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... hemopathies, solid cancers ... hepatitis • Pulmonary ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... - pulmonary opacities ... unless severe APLS ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... have fever - ACS ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... microglobulin Treatment ... workup #oncology #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... Blood cultures • CXR ... early disease) • CXR ... foreign body, cancer ... Lung #Abscess #pulmonary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... B-LNH), solid cancers ... diseases: SLE+++, Adult-onset ... #management #treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Lymphoma • Lung cancer ... characteristic features Clinical ... Tuberculosis Diagnosis ... and Culture • CXR ... disease • Check CXR
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... erythematosus (ACLE ... Differential Diagnosis ... rheumatoid arthritis, adult-onset ... • Cervical cancer
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