12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... #management #hematology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... Phlebotomy - MH/CCF ... #Management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... complete paralysis of all ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... transformation to AML ... • Parvovirus infection ... progression to AML ... factors (examples: G-CSF
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... circulation: MCA ACA ... Diagnosis: • Infection ... epilepticus Treatment ... #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... weakness, urinary retention ... : - Seen with AML ... (~20 %) and APL
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
acute coronary syndrome ... then placed on prevention ... differential #algorithm #management ... #heartfailure #chf ... icu #clinical #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Inhibitors of Na+K+2Cl ... nocturnal enuresis • Prevention ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
IDSA Recommendations for Preventing and Treating Cryptococcosis in HIV-AIDS
Treatment for cryptococcosis consists of 3 phases: induction,
Recommendations for Preventing ... and a negative CSF ... #Treatment #management ... opportunistic #infections ... #HIVAIDS #pharmacology