13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... presents with coagulation ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... defects and liver
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... defects and liver ... Obstetrics #OBGyn #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
• Vasculitis Coagulation ... deficiencies Coagulation ... Iatrogenic) • Liver ... Intravascular Coagulation ... Algorithm #Causes #Hematology
Spider Angioma: Dialated superficial arterioles, most commonly associated with advanced liver disease.

Charlie Goldberg, M.D. - UCSD
with advanced liver ... Images #Clinical #Photo ... #Dermatology #Rash
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... ) • Advanced Liver ... EricsMedicalLectures/ #Coagulation ... comparison #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... Kasabach-Merritt syndrome Coagulation ... deficiency • Liver ... #nonpalpable #dermatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... intravascular coagulation ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... DIC • Severe Liver ... Intravascular #Coagulation ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... deficiency • Liver ... the PTT suggests liver ... these causes are liver ... Acquired: • Liver
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
• Reduced liver ... #differential #hematology ... #coagulation