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differential hematology management fever hemophagocytic hlh lymphohistiocytosis acidosis anemia conjugated dengue elevation erythematosus hemeonc hemolytic hodgkins jaundice lactate lactic lupus
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... Malaria • Oxygen agents ... nitrates • Other agents ... #causes #classification ... #hematology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... or mutation in genes ... coding for bile ... #diagnosis #conjugated ... #differential #causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... Drugs, Unknown cause ... treatment #summary #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... / hypoxemia -> focus ... the offending agent ... laboratory or diagnostic ... #typeb #classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #classification ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... Lab Tests: • CBC ... #rheumatology # ... classification
Modified dengue severity classification, PAHO/WHO Dengue without warning signs - DNWS: • Person who lives or has
dengue severity classification ... include any child coming ... and no apparent focus ... fever #severity #classification ... #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... - Associated genes ... Pathophysiology ... of NK cells and CD8 ... #Management #Hematology
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... : The exact cause ... The diagnosis of ... Serial CBC counts ... #Fever #Diagnosis
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