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diagnosis hematology causes blood bruising management platelets product reactions workup afib anemia anticoagulation bleed cancer chads2 chads2vasc defects disorders hasbled
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... #Defects #comparison ... #table #differential ... #diagnosis #hematology
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... - Differential ... Diagnosis Algorithm ... vs Acquired • Platelet ... Quantitative (Thrombocytopenia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... #Causes #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... #Differential # ... #hematology #platelets
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... - History of bleeding ... epistaxis, gingival bleeding ... #Differential # ... Causes #Workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Diagnosis Algorithm ... myelosuppressive agents ... #Differential #
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... B-symptoms, bruising/bleeding ... anemia, ↑ MCV, ↑/↓ platelets ... #hematology #WBC
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... with or without platelet ... Schistocytes, thrombocytopenia ... #workup #hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
S Stroke 1 B Bleeding ... D Drugs Anti-platelet ... agent, NSAID 1 ... CHADS2VASc #HASBLED #Comparison ... AFib #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (thrombocytopenia ... are caused by bleeding ... Immunosuppressive agents ... Chemotherapeutic agents ... blood count with differential
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