21 results
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Cirrhosis - Nephrotic ... syndrome - Acute ... Drugs - SIADH Renal ... - Diuretics ... Differential #Diagnosis #Table
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... failure, Cirrhosis, Nephrotic ... syndrome) • ADH ... differential #diagnosis #table ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... losses, Diuretic ... UNa > 20: • Acute ... , UNa < 20 • Nephrotic ... #Causes #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
GI losses • Renal ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal ... #Nephrology #Differential
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
failure, Cirrhosis, Nephrotic ... syndrome - ... > 30): SIADH, Medications ... Primary polydipsia, Low ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
GI losses • Renal ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal ... #Nephrology #Differential
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Abdominal Compartment Syndrome ... , Medications Intra-Renal ... Differential #Diagnosis #nephrology ... #causes #algorithm
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
volume loss - diuretics ... liver failure • nephrotic ... syndromerenal ... Diagnosis #Workup #Algorithm ... #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute ... syndromeHyponatremia ... #Diuresis #Nephrology ... #Pharmacology #Medications ... #Table
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... mOsm/kg - Implies renal ... • Euvolemic (Low ... , Cushing syndrome ... #nephrology #sodium