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Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... Amphoterecin B, Abelcet, Ambisome ... Overview #Polyenes #Antifungal ... AmphoterecinB #Abelcet #Ambisome
Spectrum of activity for systemic antifungal agents Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... .2015.10.012 #Antifungal ... #antibiogram #management
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
meatballs appearance Management ... • Topical antifungals ... • Oral antifungal ... SkinRash #Diagnosis #Management
Rare Invasive Yeasts - Species and Antifungal Therapy Cryptococcus, Geotrichum, Kodamaea, (Pichia)ohmeri, Malassezia, Pseudozyma, Rhodotorula, Saccharomyces, Saprochaete
- Species and Antifungal ... Invasive #Yeasts #Antifungal ... #Therapy #Management
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... PMC3146381/ #Antifungal
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Antifungal Agents ... @ZhuoerXie #Antifungal ... #pharmacology #management
Common toxicities of antifungal agents. CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... #antifungal #toxicities
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
Tests Conduct antifungal ... Additional management ... Candidiasis #IC #antifungal ... #diagnosis #management
Amphotericin B - Pharmacology Summary Sheet Class: Polyene Antifungal Mechanism of Action: • Binds to ergosterol → Complexes
Class: Polyene Antifungal ... Lipid Complex), Ambisome ... #Pharmacology #ambisome
Antifungal Azoles - Antibiotics Class Overview Mechanism: inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Overview #Azoles #Antifungal
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