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differential causes management nephrology workup cardiology ddxof hematology peds em pulmonary evaluation gastroenterology pediatrics neurology endocrinology types dermatology rheumatology hepatology
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
Vasculitides #Diagnosis ... #Vessel #Size #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... antibody) - P-ANCA ... @AnnKumfer #ANCA ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... disease - MPO>PR3 - ANCA ... Antineutrophil #antibodies #diagnosis
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
ANCA, antineutrophil ... antibodies; c-ANCA ... hypertension; p-ANCA ... Glomerulonephritis #Algorithm
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA ... #Rheumatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Associated - ANCA ... Differential Diagnosis ... #differential #diagnosis ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... #differential #diagnosis ... #algorithm #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Pauci-Immune: - ANCA-positive ... polyangiitis) - ANCA-negative ... testing: anti-ANCA ... #differential #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
cytoplasmic antibody (ANCA ... ) + • c-ANCA: ... staining • p-ANCA ... Glomerulonephritis #RPGN #Classification ... #Differential #Diagnosis
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
- Differential Diagnosis ... Framework ANCA: ... • C-ANCA: GPA ... Wegener's) • P-ANCA ... #differential #diagnosis
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