10 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... #Cancer #Algorithm ... #Anticoagulation ... #Management #Hematology ... #Oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... #Anticoagulation ... #Management #Hematology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Thrombosis and Bleeding ... in Liver Disease ... #Thrombosis #Bleeding ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Acquired • Anticoagulation ... Iatrogenic) • Liver ... Coagulation #Bleeding ... Algorithm #Causes #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
2 V Vascular disease ... Abnormal renal/liver ... >2.3mg/dL) 1 Liver ... S Stroke 1 B Bleeding ... AFib #Diagnosis #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
the spleen or liver ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
ducts, commonly leading ... indications for liver ... without PSC • CANCER ... and end-stage liver ... management #summary #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... protein C and S Pathophysiology ... DIC • Severe Liver ... Disease: - Impaired ... treatment #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... night sweats, bleeding ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis