9 results
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Utilization of Antibiotics ... as Antidotes ... Valproic Acid Toxicity ... #Antidotes #Toxicology ... #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... show anion-gap metabolic ... #Salicylate #Aspirin ... #Toxicity #Toxicology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... alkalosis and metabolic ... #Toxicology #Pharmacology ... #Diagnosis #Management ... #Aspirin
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... people variably metabolize ... #Tramadol #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Syndrome (PRIS) Diagnosis ... Hyperlactatemia • Metabolic ... Syndrome #PRIS #Diagnosis ... #Management #Pharmacology ... #Toxicity #Toxicology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... : Metabolic acidosis ... #Toxicology #Phases ... #Pharmacology # ... Diagnosis
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Risperidone • Antibiotics ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
gasoline additive Pharmacology ... 1-2 mL/kg - Metabolite ... formic acid) causes toxicity ... osmolal gap #Diagnosis ... #Management #Toxicology