2919 results
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Definition: Small antigen-antibody ... If self-antigens ... are the cause: ... If bacterial antigens ... are the cause:
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mediators: lgE - Antigen ... Form: Soluble antigen ... Allergen-specific lgE causes ... Form: Cell-bound antigen ... complex - Antigen
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
• Type II - Antigenic ... cell surfaces causes ... reaction against the antigen ... small antibody-antigen ... exposure to allergen causes
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
immunity: - Antigenic ... of gonococcal antigen ... antibodies and causes ... proteases - Blocking antigen
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... Macrophage engulfs antigen ... -> Antigen presentation ... cells recognize antigen
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
• Most common cause ... media • Important cause ... 95%) • Urine antigen ... in CAP • Urine antigen
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... , worse at the bases ... reaction to inhaled antigen ... Diseases #ILD #Causes
Causes of Membranous Nephropathy (MN)
Primary (75-80%)
 • PLA2R antigen (70-80%)
 • Thrombospondin (1-5%)
Secondary (20-25%)
 • Infection
Causes of Membranous ... 80%) • PLA2R antigen ... diagnosis #nephrology #Causes
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Postulate 1 - Viral antigen-antibody ... Viral replication causes
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... , cytology/CEA antigen