55 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... • Prolonged PT/PTT ... Manifestations of DIC ... PT/INR: ↑ • PTT ... INR < 2.3 - APTT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... elevated in: • DIC ... thematttsai #PT #PTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... Prolonged PT and aPTT ... intravascular coagulation (DIC
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... intravascularcoagulation (DIC ... #Abnormal #PT #aPTT
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... aggregation PT, aPTT ... small vessels #DIC
Papilledema vs Normal Optic Disc

Blurred vs sharp optic disc margins

#Papilledema #OpticDisc #Normal #Comparison #Fundoscopy #Ophthalmology #Clinical
vs Normal Optic Disc ... vs sharp optic disc ... Comparison #Fundoscopy #Ophthalmology
Classic signs of arteritic anterior ischemic optic neuropathy or giant cell arteritis are mild arterial narrowing
and chalky white disc ... Korean Journal of Ophthalmology ... arteritis #photo #disc ... #nerve #Ophthalmology
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC
Pathological Optic Disc Cupping

Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5).

Thinning of optic disc
Pathological Optic Disc ... Note cup-to-disc ... Thinning of optic disc ... so that optic disc ... Cupping #fundoscopy #ophthalmology
Optic Disc Edema

The optic disc is elevated and its surface is covered by cotton wool spots
Optic Disc Edema ... The optic disc ... papilledema #fundoscopy #ophthalmology