23 results
diagnosis hematology treatment differential infectiousdiseases classification blood criticalcare disorders fusarium overview product reactions rheumatology shock syndrome activation adrenal anemia aplastic
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... Treat primary cause ... INR < 2.3 - APTT ... #treatment #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... procedures - Infection ... practices that could cause ... : INR/PT, aPTT(liver ... patients if the cause
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... Chronic Management
Ear Pain (Otalgia) - Differential Diagnosis Framework Primary Otalgia - Pain that originates from the ear
associated with infection ... by bacterial infections ... (90%), Fungal infections ... artery aneurysm, Pott ... Otalgia #Ear #Pain #Otology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... are caused by members ... sensitivity (sn) 82% in pts ... sn lower in SOT pts ... IA #Diagnosis #Management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... acute leukemia Management ... treatment #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Cytopenia +++ (Plt ... Still disease, Infection ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Graves Disease - Autoimmune Hyperthyroidism Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50 Diagnosis: 1 )
Epidemiology: Most common cause ... • Methimazole/PTU ... Hyperthyroidism #diagnosis #management ... #endocrinology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... bruising, bleeding, infection ... Leukemia #Hematology #Oncology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Diagnosis and Management ... : Most Common Cause ... : TB, fungal infection ... Secondary #Diagnosis #Management ... #Endocrinology
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