38 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
or APTT Artifactually ... Is a Systemic Disease ... to identify the cause ... of Prolonged APTT ... mixing #studies #PTT
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTTProlonged ... PTTProlonged ... PTTProlonged ... PTT, Normal PT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Early liver disease ... aPTT) 3. ... PT and aPTT 1. ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... PT and aPTT If ... aPTT are both prolonged ... Causes include : ... #aPTT #Prolonged
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bleeding • Prolonged ... INR • Normal aPTT ... (prolonged if very ... VonWillebrand #Disease
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... • Severe Liver Disease ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... ) • aPTT is prolonged ... mixing study (aPTT ... normal in mild cases
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/ABNORMAL PTT: ... Perform a PTT mixing ... /NORMAL PTT: Suggests ... prolonged after ... /ABNORMAL PTT:
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... : INR/PT, aPTT(liver ... disease, decrease ... bypass), LFT (liver disease
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... Activation: Liver disease ... , Kidney Disease ... Hypocalcemia #Diagnosis #Management ... #endocrinology