18 results
diagnosis treatment differential algorithm causes coagulation dic disorders disseminated intravascular oncology product reactions rheumatology thrombocytopenia workup anemia aplastic bone checklist
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... /aPTT normal • ... Differential #Diagnosis #Management ... #Algorithm #hematology
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... Intake (diet) - Activation ... Pancreatitis, Blood ... Hypocalcemia #Diagnosis #Management ... #endocrinology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... /PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
for decreased PLT ... plateletcount), peripheral blood ... , aPTT(liver disease ... or if a primary hematologic ... Causes #Workup #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... Chronic Management ... #treatment #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... acute-phase reactant Blood ... Scoring #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... ↑ PTT • ↑ Fibrin ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Management of Jehovah's Witness patient in ICU Clarify which products may be used - Discuss
Management of Jehovah's ... Minimize blood loss ... platelets, INR, PTT ... prevent ongoing blood ... #CriticalCare #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Phagocytosis of blood ... Cytopenia +++ (Plt ... Lymphohistiocytosis #diagnosis #management
Bone resorption and the relationship between osteoblasts and osteoclasts. RANK is expressed on the osteoclasts,
differentiation, and activation ... the resorptive pit ... concentration in the blood ... RANK = receptor activator ... Pathophysiology #Endocrinology
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