12 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
of Abnormal Coagulation ... - Prolonged aPTT ... - Prolonged aPTT ... #APTT #Laboratory ... #Hematology #Diagnosis
Prolonged APTT - Diagnostic Algorithm

#Prolonged #APTT #PTT #abnormal #Diagnosis #Algorithm #hematology
Prolonged APTT - ... Diagnostic Algorithm ... #Prolonged #APTT ... #PTT #abnormal ... #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
INR), Prolonged PTT ... (INR), Normal PTT ... , Normal PT (INR ... #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... /aPTT MAHA likely ... /aPTT normal • ... #Algorithm #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... • Normal platelet ... PT/INR • Normal ... aPTT (prolonged ... Disease #Diagnosis #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... PT and/or aPTT) ... Study #diagnosis #hematology ... pathophysiology #hematology ... #laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... Scoring #diagnosis #hematology ... #laboratory
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... may be normal in ... #treatment #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... be performed PT ... , PTT, and fibrinogen ... levels - Usually normal ... Diagnosis #Workup #Hematology