21 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... - Prolonged aPTT ... - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT ... #Diagnosis #Algorithm ... #Causes #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... #PTT #Prothrombin ... Thromboplastin #laboratory ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #treatment #management ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... /aPTT MAHA likely ... /aPTT normal • ... #Algorithm #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... #differential #hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Differential Diagnosis Algorithm ... • 12-13 g/dL, ... /aPTT Differential ... Differential #Diagnosis #Algorithm ... #hematology #workup
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... and aPTT 1. ... #differential #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation (DIC ... , aPTT: • Expected ... small vessels #DIC ... Scoring #diagnosis #hematology ... #laboratory
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... anti-MPO - Seen with PTU ... Discontinuation of causal ... • Laboratory ... comparison #table #rheumatology