20 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTT • Prolonged ... PTT, Normal PT ... • Prolonged PTT ... #Diagnosis #Algorithm ... #Causes #Hematology
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Tests - Prolonged PT ... - Prolonged aPTT ... and Prolonged PT ... - Prolonged aPTT ... #Laboratory #Hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... or APTT? ... to identify the cause ... prolonged #diagnosis #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... / PT - Differential ... aPTT: Intrinsic ... #PT #INR #Algorithm ... #Hematology #differential
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Thromboplastin Time (PTT ... Prothrombin Time (PT ... thematttsai #PT ... #hematology #diagnosis
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Algorithm #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... 2B) • Normal PT ... INR • Normal aPTT ... Disease #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Prothrombin Time (PT ... typically prolong PT ... #Abnormal #PT ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... INR < 2.3 - APTT ... #hematology