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diagnosis differential hematology management coagulation abnormal disorders pt treatment workup algorithm hyperthyroidism anemia aspergillus autoimmune bleeding brain bruising clinical crypto
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
or APTT Artifactually ... Is a Systemic Disease ... or APTT? ... to identify the cause ... of Prolonged APTT
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Early liver disease ... aPTT) 3. ... PT and aPTT 1. ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... PT and aPTT If ... aPTT are both prolonged ... Causes include : ... #aPTT #Prolonged
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... bleeding • Prolonged ... INR • Normal aPTT ... (prolonged if very ... VonWillebrand #Disease
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... • Severe Liver Disease ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... prolonged after ... and the PTT suggests ... discern these causes
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... ) • aPTT is prolonged ... mixing study (aPTT ... normal in mild cases
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... : INR/PT, aPTT(liver ... disease, decrease ... bypass), LFT (liver disease
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Algorithm Elevated PTH ... Hypercalcemia Low PTH ... Granulomatous Disease ... Diagnosis #Algorithm #causes ... #endocrinology
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