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differential coagulation disorders prolonged algorithm laboratory rheumatology treatment workup dic disseminated druginduced intravascular lupus mixing oncology platelet activation aggregometry anemia
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
the PT or APTT ... Prolonging the PT ... or APTT? ... to identify the cause ... #diagnosis #hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... #Diagnosis #Algorithm ... #Causes #Hematology
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Tests - Prolonged PT ... - Prolonged aPTT ... and Prolonged PT ... - Prolonged aPTT ... #Hematology #Diagnosis
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Perform a PTT mixing ... PT/NORMAL PTT: ... PT/ABNORMAL PTT
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
type 2B) • Normal ... PT/INR • Normal ... aPTT (prolonged ... VonWillebrand #Disease #Diagnosis ... #Hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
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