17 results
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Thrombosis vs Arterial ... • Nephrotic Syndrome ... Fat Emboli ARTERIAL ... septic emboli) - Myxoma ... pathophysiology #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... • APLA Alloimmune ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Hypercoagulable State Arterial ... risk actor for arterial ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL-1B, ATRA ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... • Symptoms of anemia ... • hemolytic anemia ... , Myeloma • Waldenström ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... ) (e.g. lupus, CLL ... disease, Copper and ... differential #diagnosis #hematology ... #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... • Rule out B12 and ... #Causes #Hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Evans • ITP • Cl-NH ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... Pancytopenia is a hematologic ... than 150,000 per mcL ... These causes could
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail Fold ... Iron deficiency anemia ... Mellitus Half-and-Half ... • Nephrotic syndrome ... Differential #Diagnosis #Algorithm