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diagnosis hematology differential anemia algorithm hemolytic table aflp autoimmune hellp hemolysis liver management obstetrics pregnancy blood causes cold deficiency hepatitis
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... pathophysiology #pbc #psc #hepatology ... #comparison
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... Cold agglutinin disease ... DAT #Autoimmune #Hemolysis ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... cold agglutin disease ... e.g. sickle cell disease ... Hypersplenism, Wilson's disease ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Electrolytes: Wilson's disease ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Anemia of Chronic Disease ... • Bleeding • Hemolysis ... Renal Disease, Liver ... Disease, Endocrinopathy ... Algorithm #Causes #Hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... HELLP Syndrome (Hemolysis ... clinical features: Hemolysis ... #Pregnancy #hepatology ... obstetrics #hepatitis #comparison
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... and Autoimmune Diseases ... Antibody-mediated hemolysis ... Differential #Diagnosis #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell disease ... Cold agglutinins disease ... , Hemoglobin H disease ... elliptocytosis, autoimmune hemolysis ... Algorithm #workup #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Mostly transient hemolysis ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... infection, Autoimmune diseases ... - Autoimmune diseases ... #NonHodgkins #comparison ... #differential #hematology
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