13 results
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... Lead poisoning • Macrocytic ... , Disseminated intravascular ... #differential #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... differential #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 95 (or 100) is macrocytic ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic ... #Macrocytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... idiopathic) - Autoimmune ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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and Intravascular ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Framework by MCV Microcytic ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Infections Macrocytic ... Differential #Diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Warm Antibody Autoimmune ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... Warm #Antibody #Autoimmune ... management #treatment #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... Blood smear - RBC ... CLL (older) • Autoimmune ... causing intravascular ... #hematology #diagnosis