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diagnosis differential hematology algorithm causes rheumatology management oncology approach classification dermatology joint msk pain signs systemic clinical cll gastroenterology generalized
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... , Liver disease, ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... hematology #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... , Liver diseases ... Thalassemia, Liver diseases ... cells - Renal diseases ... , Liver diseases
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Non-lmmune #Anemia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... - Anemia of chronic ... of chronic kidney ... disease - Vitamin ... #differential #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell disease ... Cold agglutinins disease ... , Hemoglobin H disease ... Diagnosis #Algorithm #workup
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... of chronic inflammation ... deficiencies: Chronic ... kidney disease, ... , Intrinsic RBC
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... Connective Tissue Disease ... connective tissue disease ... bronchiolitis-interstitial lung disease ... Interstitial #Lung #Diseases
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Cardio-pulmonary disease ... • Anemia • ... Chronic Infection ... Deconditioning • Arthritis ... • Endocrine Disease
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... disorders • Celiac disease ... Iron deficiency anemia
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... : • Acute or chronic ... necrosis, and Paget disease ... rheumatology #approach #workup
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