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diagnosis differential algorithm rheumatology causes management oncology approach classification dermatology joint msk pain systemic cll generalized leukemia lupus lymphocytic morphology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... differential #diagnosis #hematology ... #microscopy #atlas
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... coagulopathy (DIC) #RBC ... #Morphology #Atlas ... #differential #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Anemia of chronic ... of chronic kidney ... disease - Vitamin ... Underproduction #Algorithm #hematology ... #differential #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... disorders • Celiac disease ... Iron deficiency anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Chronic ... kidney disease, ... , Intrinsic RBC ... Production #Index #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Diagnosis #Algorithm #workup ... #hematology #testing
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... Obstructive Pulmonary Disease ... Idiopathic • Chronic
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