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hematology algorithm causes oncology classification hemolytic rheumatology approach arthritis laboratory leukemia lymphocytic management testing abg acid acidbase agglutinin base blood
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... , Chronic disease ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... - CD7, CD3 Chronic ... - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Atlas • Microcytic ... #Morphology #Atlas ... #key #diagnosis ... #differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... other reproducible morphologic ... membrane disorder ... #workup #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Anemia of chronic ... disease - Vitamin ... Probable bone marrow disorder ... #differential # ... workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... • Symptoms of anemia ... anemia • Cold ... Blood smear - RBC ... younger pts) Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... kidney disease, ... , Intrinsic RBC ... #differential # ... diagnosis #calculation
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