42 results
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
- Species and Antifungal ... Trichosporon, Candida auris ... Invasive #Yeasts #Antifungal
Invasive Candidiasis (IC)

Diagnosis:
Culture:
 • Gold standard, but Slow (~2-3 days), 50% sensitivity
 • Blood Sample
 •
Tests Conduct antifungal ... Candidiasis #IC #antifungal ... management #candida #auris
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... .2015.10.012 #Antifungal
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
Management • Topical antifungals ... • Oral antifungal
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... PMC3146381/ #Antifungal
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... #antifungal #toxicities
Antifungal Agents Frequently Used in Leukemia
Antibiogram:
 • Fluconazole
 • Itraconazole
 • Voriconazole
 • Posaconazole
 • Caspofungin
Antifungal Agents ... @ZhuoerXie #Antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... Overview #Polyenes #Antifungal
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Overview #Azoles #Antifungal
Antifungal Organ System Tissue Penetration

Concentrations in tissues and body fluids for each systemic antifungal agent relative
Antifungal Organ ... each systemic antifungal ... #Antifungal #OrganSystem