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differential hematology anemia classification hyperbilirubinemia macrocytic aafp approach bilirubinemia congenital conjugated direct folate folicacid hemolytic hepatitis homocysteine inherited injury jaundice
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased Serum bilirubin ... #Causes #Workup ... #Hematology #Diagnosis
Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... or non-hemolytic ... #Diagnosis #Peds ... Neonatal #Jaundice #Algorithm ... #Differential #Workup
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Algorithm 1. ... non-ICU vs ICU causes ... Hyperbilirubinemia #direct #bilirubin ... #Algorithm #gastroenterology ... #hepatology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Algorithm • 12 ... /uL Initial Workup ... ↑ Destruction (hemolysis ... #Algorithm #hematology ... #workup
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... Hemorrhage or hemolysis ... the most likely cause ... #Diagnosis #Macrocytosis ... #Workup #AAFP
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... (>100 fL) • B12 ... #Algorithm #Causes ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... decrease in most cases ... anemia Indirect bilirubin ... #Workup #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood ... Deficiency • B12 ... Increased Unconjugated Bilirubin ... #Algorithm #Causes ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... #hepatology #diagnosis ... #gastroenterology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... (EPO), iron or B12 ... #Diagnosis #Workup ... #Hematology #Microcytic
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