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diagnosis hematology differential management classification thrombocytosis aafp anosmia approach bacilliformis bartonella celiac cll coccidioides coccidioidomycosis dysfunction fever fungal hodgkins hyposmia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... disease - Vitamin ... B12 and/or folate ... #differential #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Deficiency • B12 ... Deficiency • Aplastic ... of Chronic Disease ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... of Chronic Disease ... of Chronic Disease ... (>100 fL) • B12 ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... anemia Treatment ... #Anemia #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... #gastroenterology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... #oncology #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Fever Hematologic disease ... caused by Bartonella ... Incubation period: 3-12 ... severe hemolytic anemia ... TREATMENT: ​• Acute
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